Sink or Swim: Know When It’s Time to Bail

Life vest: sink or swim.

Sink or swim--clinicians don't often counsel on drowning prevention.

OBJECTIVE Drowning is one of the leading causes of injury death for young children in the United States. This study examined primary care providers' knowledge of and counseling on drowning prevention. METHODS A random sample of 465 Los Angeles County pediatricians, family physicians, and pediatric nurse practitioners who serve families with young children received mailed questionnaires; 325 (...

A sea of standards for omics data: sink or swim?

In the era of Big Data, omic-scale technologies, and increasing calls for data sharing, it is generally agreed that the use of community-developed, open data standards is critical. Far less agreed upon is exactly which data standards should be used, the criteria by which one should choose a standard, or even what constitutes a data standard. It is impossible simply to choose a domain and have i...

Hip fractures--when to nail and when to bail.

You got to know when to hold (or unfold) 'em….

In this issue of Molecular Cell, Hoffmann et al. (2012) demonstrate that the ribosome-associated bacterial chaperone Trigger Factor assists in the maturation of ribosome-attached nascent chains by acting as both a holdase and an unfoldase.